2-(4-Nitrophenyl)propionic acid → 4-Aminohydratropic acid

Beteiligte Stoffe

Reaktionsschritte

A mixture of 1 (6.7 g, 1 mmol) in THF (100 ml) and EtOH (100 ml) is slowly added 10% Pd/C (680 mg) at room temperature. The reaction mixture is hydrogenated for 24 h with H2 balloon at room temperature. The mixture is filtered through celite pad and washed with EtOH. The filtrate is concentrated in vacuo.

Herkunft & Nachweise