HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Azobisisobutyronitrile → Bromo-(2-iodophenyl)-acetic Acid Methyl Ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Azobisisobutyronitrile | HCID 6547 | — |
| Edukt | N-bromobutanimide | HCID 67184 | — |
| Edukt | Methyl 2-(2-iodophenyl)acetate | HCID 640185 | — |
| Lösungsmittel | Carbon Tetrachloride | HCID 5943 | — |
| Produkt | Bromo-(2-iodophenyl)-acetic Acid Methyl Ester | HCID 86632576 | — |
Reaktionsschritte
A mixture of (2-iodophenyl)-acetic acid methyl ester (14.5 g, 52.5 mmol), NBS (18.7 g, 105 mmol) and AIBN (1.72 g, 10.5 mmol) in CCl4 (300 mL) is refluxed for 10 h. The mixture is cooled to RT and the precipitate filtered. The filtrate is evaporated to give the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08084448B2 |
| Quelldatensatz | uspto-grants-2011_12 |
| ORD ID | ord-db93df6fcc214a318294e7c39ea96e68 |
| Quellennotiz | uspto-grants-2011_12 |