Ammonia → HCID 67499901, Verbindung

Reaktionsgleichung

[F:1][C:2]1[C:3]([C:8]2([F:18])[CH2:17][CH2:16][C:11]3(OCC[O:12]3)[CH2:10][CH2:9]2)=[N:4][CH:5]=[CH:6][CH:7]=1.ClC1C(C2(F)CCC3(OCCO3)CC2)=NC=CC=1.N>>[F:18][C:8]1([C:3]2[C:2]([F:1])=[CH:7][CH:6]=[CH:5][N:4]=2)[CH2:9][CH2:10][C:11](=[O:12])[CH2:16][CH2:17]1

Komponenten

Edukt 3

HCID 222Ammonia

HCID 67499172HCID 67499172, Verbindung

HCID 67499484HCID 67499484, Verbindung

Produkt 1

HCID 67499901HCID 67499901, Verbindung

Versuchsvorschrift

The title compound was prepared using the procedure as described in Example 1C, except for substituting the product of Example 15B for the product of Example 1B. 1H NMR (300 MHz, DMSO-d6) δ 8.41 (m, 1H), 7.80 (m, 1H), 7.56 (m, 1H), 2.80-2.22 (m, 8H). MS (DCI/NH3) m/e 212 (M+H)+.

Quellen und Nachweise

ORD-Eintrag: ord-81b32c54ce774a79abe4160314a109ac
Quelldatensatz: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08084616B2

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