Dimethylformamide dimethyl acetal → 1,4,8-Triazatricyclo[6.3.1.04,12]dodecane

HRID 66218

Reaktionsgleichung

Reaktionsgleichung von HRID 66218
[NH:1]1[CH2:11][CH2:10][CH2:9][NH:8][CH2:7][CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[CH3:12]OC(OC)N(C)C>>[N:1]12[CH:12]3[N:4]([CH2:5][CH2:6][CH2:7][N:8]3[CH2:9][CH2:10][CH2:11]1)[CH2:3][CH2:2]2

Komponenten

3

Edukt 2

HCID 78373Dimethylformamide dimethyl acetalHCID 3987421,4,8-Triazacycloundecane

Produkt 1

HCID 126416581,4,8-Triazatricyclo[6.3.1.04,12]dodecaneAusbeute 81,8 %

Versuchsvorschrift

In a manner similar to that of Example 1 (C), 5.28 g (33.6 mmol) of 1,4,8-triazacycloundecane and 4.00 g of dimethylformamide dimethyl acetal were reacted to give 4.59 g of 1,4,8-triazatricyclo[6.3.1.04,12 ]dodecane as a clear, colorless liquid, bp 80°-82° (three fractions) (1.2 mm), nD24 = 1.5182. A fraction boiling at 82° was analyzed.

Quellen und Nachweise

ORD-Eintrag
ord-141a818fb3f74ff09394c0b370e6a40e
Quelldatensatz
uspto-grants-1978_12
Patentnummer
US04130715

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