Zurück
HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 66351Erstellt: 25. Oktober 2026

2-(3-Nitrophenyl)oxazolo[4,5-b]pyridine → 3-(Oxazolo[4,5-b]pyridin-2-yl)aniline

https://huagongshe.com/reaction/66351

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-(3-Nitrophenyl)oxazolo[4,5-b]pyridineHCID 12461374—
KatalysatorPalladiumHCID 23938—
LösungsmittelEthanolHCID 702—
Produkt3-(Oxazolo[4,5-b]pyridin-2-yl)anilineHCID 611086—

Reaktionsschritte

A mixture of 700mg. of 2-(3-nitrophenyl)oxazolo[4,5-b]pyridine in 50 ml. of ethanol was hydrogenated over 150 mg. of 5% palladium-on-carbon catalyst. The catalyst was removed by filtration and the solvent was concentrated to dryness. The residue was recrystallized from chloroform-petroleum ether to give 2-(3-aminophenyl)oxazolo[4,5-b]pyridine, m.p. 179°-180.5° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04131677
Quelldatensatzuspto-grants-1978_12
ORD IDord-08c5e003bb1e44bfb83ec6053d9066fd
Quellennotizuspto-grants-1978_12