Dichloromethane → 8-Fluoro-4-[3-(3-methyl-isoxazol-5-yl)-phenyl]-7-pyrrolidin-1-yl-1,3-dihydro-benzo[b][1,4]diazepin-2-one

Reaktionsgleichung

[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:20][C:21]([CH2:22][C:23](=[O:5])[c:25]2[cH:26][c:27](-[c:31]3[cH:32][c:33]([CH3:36])[n:34][o:35]3)[cH:28][cH:29][cH:30]2)=[O:37])[cH:10][c:11]([F:19])[c:12]([N:14]2[CH2:15][CH2:16][CH2:17][CH2:18]2)[cH:13]1)([CH3:6])([CH3:24])[CH3:38].[Cl:46][CH2:47][Cl:48].[F:39][C:40]([F:41])([F:42])[C:43]([OH:44])=[O:45]>>[N:7]1=[C:23]([c:25]2[cH:26][c:27](-[c:31]3[cH:32][c:33]([CH3:36])[n:34][o:35]3)[cH:28][cH:29][cH:30]2)[CH2:22][C:21](=[O:37])[NH:20][c:9]2[c:8]1[cH:13][c:12]([N:14]1[CH2:15][CH2:16][CH2:17][CH2:18]1)[c:11]([F:19])[cH:10]2