Methyl iodide → 2-Imino-3,5-dimethyl-4-(1,3,4)-thiadiazoline hydroiodide

HRID 66563

Reaktionsgleichung

Reaktionsgleichung von HRID 66563
[CH3:1][I:2].[NH2:3][C:4]1[S:5][C:6]([CH3:9])=[N:7][N:8]=1>C(O)(C)C>[IH:2].[NH:3]=[C:4]1[N:8]([CH3:1])[N:7]=[C:6]([CH3:9])[S:5]1

Komponenten

4

Edukt 2

HCID 6328Methyl iodideHCID 669491,3,4-Thiadiazole, 2-amino-5-methyl-

Produkt 1

HCID 705411252-Imino-3,5-dimethyl-4-(1,3,4)-thiadiazoline hydroiodide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3776IsopropanolLösungsmittel

Versuchsvorschrift

64.1 g of methyl iodide are added to a solution of 17.6 g of 2-amino-5-methyl-1,3,4-thiadiazole in 350 ml isopropanol. The solution is refluxed for 15 hours. The reaction mixture is then evaporated to dryness, the crystalline evaporation residue is stirred with ethyl acetate and the solvent is filtered off with suction. The crystalline residue is washed, first with ethyl acetate and then with ether, and then dried. 2-Imino-3,5-dimethyl-4-(1,3,4) -thiadiazoline hydroiodide with a melting point of 208° (decomposition) is thus obtained.

Aufarbeitung

  1. temperatureThe solution is refluxed for 15 hours
  2. customThe reaction mixture is then evaporated to dryness
  3. filtrationthe solvent is filtered off with suction
  4. washThe crystalline residue is washed, first with ethyl acetate
  5. dry with materialwith ether, and then dried

Quellen und Nachweise

ORD-Eintrag
ord-bf3f6cd9eeb340b9976ab9527da93279
Quelldatensatz
uspto-grants-1982_08
Patentnummer
US04342764

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