HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Methylindole → 5-Hydroxy-5-(1-methyl-3-indolyl)-2,4,6-(1H,3H,5H)pyrimidinetrione
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Methylindole | HCID 11781 | — |
| Edukt | 2,4,5,6(1H,3H)-Pyrimidinetetrone, monohydrate | HCID 16723 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 5-Hydroxy-5-(1-methyl-3-indolyl)-2,4,6-(1H,3H,5H)pyrimidinetrione | HCID 21271250 | — |
Reaktionsschritte
Alloxan hydrate (1.6 g., 0.01 mole) 1-methylindole (1.3 g., 0.01 mole) and ethanol (50 ml.) was combined and the mixture refluxed for 0.5 hour, then concentrated to half-volume, diluted with water and the resulting product recovered by filtration [2.7 g., Rf 0.5 (1:1 ethyl acetate:hexane/5% acetic acid)].
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04342771 |
| Quelldatensatz | uspto-grants-1982_08 |
| ORD ID | ord-b905210002c446778598a5214583d97f |
| Quellennotiz | uspto-grants-1982_08 |