2,2,2-Trichloroethanimidamide → HCID 178516502, Verbindung

HRID 66713

Reaktionsgleichung

C(=O)(OC1N=CC=CN=1)N.[Cl:11][C:12]([Cl:17])([Cl:16])[C:13]([NH2:15])=[NH:14].[C:18]([O-])(=O)[CH2:19][C:20](C)=[O:21]>>[OH:21][C:20]1[CH:19]=[CH:18][N:15]=[C:13]([C:12]([Cl:17])([Cl:16])[Cl:11])[N:14]=1

Komponenten

Edukt 3

HCID 356082,2,2-Trichloroethanimidamide

HCID 6971017Acetoacetate

HCID 54270844Pyrimidinyl carbamate

Produkt 1

HCID 178516502HCID 178516502, Verbindung

Versuchsvorschrift

The pyrimidinyl carbamate compounds of the present invention may be prepared by reacting trichloroacetamidine with the corresponding acetoacetate to form the corresponding 4-hydroxy-2-trichloromethylpyrimidine, which is then reacted with a selected carbamoyl chloride. These general reactions are illustrated below in equations (A) and (B). In equation (A), trichloroacetamidine is reacted with methylacetoacetate to form 4-hydroxy-6-methyl-2-trichloromethylpyrimidine. In equation (B), the 4-hydroxy-6-methyl-2-trichloromethylpyrimidine is reacted with dimethylcarbamoyl chloride to form 6-methyl-2-trichloromethyl-4-pyrimidinyl dimethylcarbamate. ##STR3##

Quellen und Nachweise

ORD-Eintrag: ord-fa375f70ac0e4887b51c5e9492a4cc48
Quelldatensatz: uspto-grants-1982_08
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US04343803

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