HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methanol → 3,5-Dimethoxypyrazin-2-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methanol | HCID 887 | — |
| Edukt | Sodium | HCID 5360545 | — |
| Edukt | 2-Amino-5-bromo-3-methoxypyrazine | HCID 11344724 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 3,5-Dimethoxypyrazin-2-amine | HCID 20528923 | — |
Reaktionsschritte
A mixture of 0.1 mole of 2-amino-3-methoxy-5-bromopyrazine and 0.1 mole of sodium in 160 ml. of anhydrous methanol is refluxed 5-10 hours and poured into water. The product is extracted with ether or chloroform and recrystallized from a suitable solvent such as ethanol to give 2-amino-3,5-dimethoxypyrazine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04343802 |
| Quelldatensatz | uspto-grants-1982_08 |
| ORD ID | ord-e7563763c7f34dd39423bae8421d0059 |
| Quellennotiz | uspto-grants-1982_08 |