2-Pentanone → 1-Bromo-trans-1-octen-3-one
Reaktionsgleichung
Cl/[CH:2]=[CH:3]/[C:4](=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].[Br-:11].[Li+].CC(=O)CCC>>[Br:11]/[CH:2]=[CH:3]/[C:4](=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]Komponenten
4
Versuchsvorschrift
A mixture of 68.0 g. (0.424 mole) of 1-chloro-trans-1-octen-3 one (Example 723) and 444 g. (4.24 moles) of anhydrous lithium bromide in 900 ml. of 2-pentanone is refluxed for 30 minutes, cooled, and partitioned between ice water and ether. The organic phase is washed with water and saturated brine, dried (NaSO4), and evaporated to an oil. This material is used directly without purification.
Aufarbeitung
- additionA mixture of 68.0 g
- temperaturecooled
- custompartitioned between ice water and ether
- washThe organic phase is washed with water and saturated brine
- dry with materialdried (NaSO4)
- customevaporated to an oil
- customThis material is used directly without purification
Quellen und Nachweise
- ORD-Eintrag
- ord-8fa867cbcf20417ab9d4d032eb2d0c3c
- Quelldatensatz
- uspto-grants-1982_08
- Patentnummer
- US04343949
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