Thionyl Chloride → 6,7-Dihydroxy-4-oxo-4H-1-benzopyran-3-carbonyl chloride

HRID 67094Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 67094
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[OH:12])[O:8][CH:7]=[C:6]([C:13](O)=[O:14])[C:5]2=[O:16].S(Cl)([Cl:19])=O>>[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[OH:12])[O:8][CH:7]=[C:6]([C:13]([Cl:19])=[O:14])[C:5]2=[O:16]

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 122007766,7-Dihydroxychromon-3-carboxylic acid

Produkt 1

HCID 127657576,7-Dihydroxy-4-oxo-4H-1-benzopyran-3-carbonyl chloride

Versuchsvorschrift

6,7-Dihydroxychromon-3-carboxylic acid (888 mg) together with thionyl chloride (25 ml) were refluxed for one hour. Any unreacted thionyl chloride was then removed from the reaction mixture by distillation. Benzene was added to the residue, and the mixture was subjected to distillation. The residue was triturated with dichloromethane to obtain the desired product (719 mg).

Aufarbeitung

  1. customAny unreacted thionyl chloride was then removed from the reaction mixture by distillation
  2. additionBenzene was added to the residue
  3. distillationthe mixture was subjected to distillation
  4. customThe residue was triturated with dichloromethane

Quellen und Nachweise

ORD-Eintrag
ord-64df3025169449458472a78897e73697
Quelldatensatz
uspto-grants-1982_08
Patentnummer
US04344944

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