4-Nitrophenyl chloroacetate → HCID 15754641, Verbindung

HRID 67101

Reaktionsgleichung

Reaktionsgleichung von HRID 67101
[NH2:1][C:2]1[S:3][C:4]2[C:5](=[CH:7][C:8]3[N:9]=[C:10]([NH2:14])[S:11][C:12]=3[CH:13]=2)[N:6]=1.[Cl:15][CH2:16][C:17]([O:19]C1C=CC([N+]([O-])=O)=CC=1)=O>O1CCOCC1>[Cl:15][CH2:16][C:17]([NH:14][C:10]1[S:11][C:12]2[C:8](=[CH:7][C:5]3[N:6]=[C:2]([NH:1][C:17](=[O:19])[CH2:16][Cl:15])[S:3][C:4]=3[CH:13]=2)[N:9]=1)=[O:19]

Komponenten

4

Edukt 2

HCID 949174-Nitrophenyl chloroacetateHCID 844005ST076754

Produkt 1

HCID 15754641HCID 15754641, VerbindungAusbeute 93 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

A mixture consisting of 222 mgm of 2,6-diamino-benzo[1,2-d:5,4-d']bisthiazole, 500 mgm of p-nitro-phenyl chloroacetate and 5 ml of dioxane were refluxed for 15 minutes. The reaction mixture was allowed to cool, and the crystalline substance which had separated out was filtered off, washed and dried. 350 mgm (93% of theory) of 2,6-bis-(chloroacetyl-amino)-benzo[1,2-d:5,4-d']bisthiazole, M.P. 330° C., were obtained.

Aufarbeitung

  1. temperaturewere refluxed for 15 minutes
  2. temperatureto cool
  3. customthe crystalline substance which had separated out
  4. filtrationwas filtered off
  5. washwashed
  6. customdried

Quellen und Nachweise

ORD-Eintrag
ord-d9a630a06f58499e841f82342f7220a8
Quelldatensatz
uspto-grants-1982_08
Patentnummer
US04344946

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