Toluene-4-sulfonic acid methylcarbamoyl-phenyl-methyl ester → 3-Ethyl-7-(methylcarbamoyl-phenyl-methyl)-8-[2-(4-trifluoromethyl-phenyl)-ethyl]-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine-1-carboxylic acid methylamide

Reaktionsgleichung

[CH3:1][NH:2][C:3](=[O:4])[c:5]1[n:6][c:7]([CH2:26][CH3:27])[n:8]2[c:9]1[CH:10]([CH2:14][CH2:15][c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1)[NH:11][CH2:12][CH2:13]2.[CH3:28][NH:29][C:30](=[O:31])[CH:32]([c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1)[O:39][S:40]([c:41]1[cH:42][cH:43][c:44]([CH3:45])[cH:46][cH:47]1)(=[O:48])=[O:49]>>[CH3:1][NH:2][C:3](=[O:4])[c:5]1[n:6][c:7]([CH2:26][CH3:27])[n:8]2[c:9]1[CH:10]([CH2:14][CH2:15][c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1)[N:11]([CH:32]([C:30]([NH:29][CH3:28])=[O:31])[c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1)[CH2:12][CH2:13]2