Dichloromethane → 8-(2-Chloro-benzenesulfonyl)-2-[4-(3-fluoro-oxetan-3-yl)-phenyl]-2,8-diaza-spiro[4.5]decan-1-one

Reaktionsgleichung

[CH2:33]([N:34]([S:35]([F:36])([F:37])[F:39])[CH2:38][CH3:40])[CH3:41].[Cl:1][c:2]1[c:3]([S:8](=[O:9])(=[O:10])[N:11]2[CH2:12][CH2:13][C:14]3([CH2:15][CH2:16][N:17]([c:20]4[cH:21][cH:22][c:23]([C:26]5([OH:30])[CH2:27][O:28][CH2:29]5)[cH:24][cH:25]4)[C:18]3=[O:19])[CH2:31][CH2:32]2)[cH:4][cH:5][cH:6][cH:7]1.[Cl:42][CH2:43][Cl:44]>>[Cl:1][c:2]1[c:3]([S:8](=[O:9])(=[O:10])[N:11]2[CH2:12][CH2:13][C:14]3([CH2:15][CH2:16][N:17]([c:20]4[cH:21][cH:22][c:23]([C:26]5([F:39])[CH2:27][O:28][CH2:29]5)[cH:24][cH:25]4)[C:18]3=[O:19])[CH2:31][CH2:32]2)[cH:4][cH:5][cH:6][cH:7]1