(4-Phenyl-but-3-ynyl)-carbamic acid tert-butyl ester → 4-Phenyl-but-3-ynylamine

HRID 6724

Reaktionsgleichung

Reaktionsgleichung von HRID 6724
C(OC(=O)[NH:7][CH2:8][CH2:9][C:10]#[C:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)(C)(C)C>FC(F)(F)C(O)=O.ClCCl>[C:12]1([C:11]#[C:10][CH2:9][CH2:8][NH2:7])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Komponenten

3

Edukt 1

HCID 23544319(4-Phenyl-but-3-ynyl)-carbamic acid tert-butyl ester

Produkt 1

HCID 156429914-Phenyl-but-3-ynylamine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 21863450Trifluoroacetic acid methylene chlorideLösungsmittel

Versuchsvorschrift

A solution of (4-phenyl-but-3-ynyl)-carbamic acid tert-butyl ester (98 mg) was stirred for 0.5 h in 1:1 trifluoroacetic acid/dichloromethane (10 ml). The volatile materials were evaporated to give the crude 4-phenyl-but-3-ynylamine, which was used in subsequent transformations without further purification.

Aufarbeitung

  1. customThe volatile materials were evaporated

Quellen und Nachweise

ORD-Eintrag
ord-20d2e46c1d1247a2976c93d528f9a3be
Quelldatensatz
uspto-grants-2006_08
Patentnummer
US07084154B2

Verknüpfte Notizen

Wird geladen…