Hydrochloric Acid → 6-Methyl-4-oxo-1-phenyl-1,4-dihydropyridazine-3-carboxylic acid

Beteiligte Stoffe

Reaktionsschritte

In a separate flask; 9.08 g of aniline is mixed with 37.5 ml of concentrated hydrochloric acid and 47 ml of water. The resulting solution is maintained at about 5° to 10° and a solution of 7.13 g of sodium nitrite in 24 ml of water is added. The resulting solution of phenyldiazonium chloride is added dropwise to the stirred pyrone solution, while maintaining a temperature of about 5° to 10°. The pH is maintained at about 8 to 9 by the addition of small amounts of sodium hydroxide solution.

Herkunft & Nachweise