HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 67471Erstellt: 24. Oktober 2026
Sarcosine → 3,4-dihydro-4,6-dimethyl-2H-1,4-benzodiazepine-2,5(1H)-dione
https://huagongshe.com/de/reaction/67471
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Sarcosine | HCID 1088 | — |
| Edukt | 5-methyl-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione | HCID 10487522 | — |
| Lösungsmittel | Dimethyl Sulfoxide | HCID 679 | — |
| Produkt | 3,4-dihydro-4,6-dimethyl-2H-1,4-benzodiazepine-2,5(1H)-dione | HCID 21708975 | — |
Reaktionsschritte
A mixture of 14.0 g (79 mmol) of 6-methylisatoic acid anhydride, 7.04 g (79 mmol) of sarcosine and 80 ml of dimethyl sulphoxide is stirred at 110° C. for 3 hours. The red coloured solution is evaporated in a high vacuum. The residue is treated with 80 ml of ethanol, the product crystallising out. There is obtained 3,4-dihydro-4,6-dimethyl-2H-1,4-benzodiazepine-2,5(1H)-dione of melting point 200°-202° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US04346034 |
|---|
| Quelldatensatz | uspto-grants-1982_08 |
|---|
| ORD ID | ord-286c6fc2f25a43d8ba2176baee36fbc1 |
|---|
| Quellennotiz | uspto-grants-1982_08 |
|---|
