Acetone → HCID 178482500, Verbindung

HRID 67733

Reaktionsgleichung

Reaktionsgleichung von HRID 67733
[CH3:1][NH:2][C:3](=[S:6])[NH:4][NH2:5].[CH3:7][C:8]([CH3:10])=O.[F:11][C:12]([F:23])([F:22])[C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][CH:21]=1)[C:16](Cl)=[O:17]>N1C=CC=CC=1>[CH3:7][C:8]1([CH3:10])[S:6][C:3]([NH:2][CH3:1])=[N:4][N:5]1[C:16](=[O:17])[C:15]1[CH:19]=[CH:20][CH:21]=[C:13]([C:12]([F:23])([F:22])[F:11])[CH:14]=1

Komponenten

5

Edukt 3

HCID 180AcetoneHCID 752573-(Trifluoromethyl)benzoyl chlorideHCID 2723853N-Methylhydrazinecarbothioamide

Produkt 1

HCID 178482500HCID 178482500, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

A 42 g. portion of 4-methylthiosemicarbazide was reacted with 200 ml. of acetone, and then with 32 g. of pyridine and 83.6 g. of 3-trifluoromethylbenzoyl chloride. The mixture was worked-up as described in Example 1 to obtain 77.5 g. of the desired product, m.p. 111°-115°, after recrystallization from nitromethane.

Aufarbeitung

  1. customto obtain 77.5 g
  2. customof the desired product, m.p. 111°-115°, after recrystallization from nitromethane

Quellen und Nachweise

ORD-Eintrag
ord-bd0437614152434bb4e32c1135ec93de
Quelldatensatz
uspto-grants-1982_08
Patentnummer
US04346225

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