HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Chlorobenzoic Acid → Thionyl Chloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Chlorobenzoic Acid | HCID 447 | — |
| Edukt | 2-Amino-2-methyl-1-propanol | HCID 11807 | — |
| Edukt | Thionyl Chloride | HCID 24386 | — |
| Edukt | Benzoyl chloride, 3-chloro- | HCID 69252 | — |
| Produkt | Thionyl Chloride | HCID 24386 | — |
| Produkt | Oxazole, 2-(3-chlorophenyl)-4,5-dihydro-4,4-dimethyl- | HCID 10798476 | — |
Reaktionsschritte
2-(3-Chlorophenyl)-4,4-dimethyl-2-oxazoline was prepared from 3-chlorobenzoic acid by reaction with thionyl chloride to give 3-chlorobenzoylchloride, reaction of this acid chloride with 2-amino-2-methylpropanol to give the amide and cyclization of the amide with thionyl chloride followed by neutralization with dilute sodium hydroxide to give 2-(3-chlorophenyl)-4,4-dimethyl-2-oxazoline.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04347177 |
| Quelldatensatz | uspto-grants-1982_08 |
| ORD ID | ord-fc3e60aa365a45c59398a6faf9402290 |
| Quellennotiz | uspto-grants-1982_08 |