1,4-Dichlorobenzene → 2-Bromo-1,4-dichlorobenzene

HRID 68021

Reaktionsgleichung

Reaktionsgleichung von HRID 68021
[Cl-].[Al+3].[Cl-].[Cl-].[Br:5]C1C=CC=CC=1.[CH:12]1[C:17]([Cl:18])=[CH:16][CH:15]=[C:14]([Cl:19])[CH:13]=1.[Br:20][C:21]1[CH:26]=[CH:25][C:24]([Cl:27])=[C:23]([Cl:28])[C:22]=1[Br:29]>[Fe]>[Br:29][C:22]1[CH:21]=[CH:26][C:25]([Cl:18])=[CH:24][C:23]=1[Cl:28].[Br:5][C:15]1[CH:16]=[C:17]([Cl:18])[CH:12]=[CH:13][C:14]=1[Cl:19].[Br:20][C:21]1[CH:26]=[CH:25][C:24]([Cl:27])=[C:23]([Cl:28])[CH:22]=1

Komponenten

8

Edukt 4

HCID 46851,4-DichlorobenzeneHCID 7961BromobenzeneHCID 6451240Aluminum(III) ChlorideHCID 140296631,2-dibromo-3,4-dichlorobenzene

Produkt 3

HCID 150332-Bromo-1,4-dichlorobenzeneHCID 290134-Bromo-1,2-dichlorobenzeneHCID 709471-Bromo-2,4-dichlorobenzene

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23925IronKatalysator

Versuchsvorschrift

The o-, m- or p-dichlorobenzenes or mixture thereof which is used as intermediates for syntheses of various organic compounds is brominated at 0° to 100° C. in the presence of aluminum chloride, ferric chloride or iron powder. The bromobenzene is chlorinated in the same condition. The dichlorobenzene is reacted with the dibromodichlorobenzene in the presence of an aluminum halide for 1 to 5 hours. In these methods, 1-bromo-2,4-dichlorobenzene, 1-bromo-2,5-dichlorobenzene, and 1-bromo-3,4-dichlorobenzene etc. can be obtained in high yield.

Quellen und Nachweise

ORD-Eintrag
ord-12b808519d014a45884e6fff12f972d8
Quelldatensatz
uspto-grants-1982_08
Patentnummer
US04347390

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