N-ethyl-3-methyl-6-nitroquinolin-2-amine → n2-Ethyl-3-methylquinoline-2.6-diamine

HRID 6806

Reaktionsgleichung

Reaktionsgleichung von HRID 6806
[CH2:1]([NH:3][C:4]1[C:13]([CH3:14])=[CH:12][C:11]2[C:6](=[CH:7][CH:8]=[C:9]([N+:15]([O-])=O)[CH:10]=2)[N:5]=1)[CH3:2]>CO.[Pt]=O>[CH2:1]([NH:3][C:4]1[C:13]([CH3:14])=[CH:12][C:11]2[C:6](=[CH:7][CH:8]=[C:9]([NH2:15])[CH:10]=2)[N:5]=1)[CH3:2]

Komponenten

4

Edukt 1

HCID 22018880N-ethyl-3-methyl-6-nitroquinolin-2-amine

Produkt 1

HCID 85837566n2-Ethyl-3-methylquinoline-2.6-diamine

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 82844Platinum oxide (PtO)KatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

The product (0.8 g) of Step B and platinum oxide on carbon (˜80 mg) was suspended in methanol. The resulting mixture was hydrogenated at 50 PSI for 1 h. The reaction mixture was filtered through filter aid and the solvent removed under vacuum to afford the product, which was used without further purification.

Aufarbeitung

  1. filtrationThe reaction mixture was filtered
  2. filtrationthrough filter aid
  3. customthe solvent removed under vacuum
  4. customto afford the product, which
  5. customwas used without further purification

Quellen und Nachweise

ORD-Eintrag
ord-bc1ae466ad6d421a8c6e6bc08d31abd8
Quelldatensatz
uspto-grants-2006_08
Patentnummer
US07084156B2

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