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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 68763Erstellt: 24. Oktober 2026

1,4-Dioxa-8-aza-spiro[4.5]decane-8-carbonitrile → 1-(3-Isopropyl-1,2,4-oxadiazol-5-YL)piperidin-4-one

https://huagongshe.com/de/reaction/68763

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1,4-Dioxa-8-aza-spiro[4.5]decane-8-carbonitrileHCID 86678210—
EduktHCID 178449908HCID 178449908—
Produkt1-(3-Isopropyl-1,2,4-oxadiazol-5-YL)piperidin-4-oneHCID 66915348—

Reaktionsschritte

The title compound is prepared from 1,4-dioxa-8-aza-spiro[4.5]decane-8-carbonitrile and N-hydroxy-isobutyramidine following a procedure analogous to that described in Intermediate 5. LC (method 6): tR=1.56 min; Mass spectrum (ESI+): m/z=254 [M+H]+.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08822471B2
Quelldatensatzuspto-grants-2014_09
ORD IDord-ad2d13b10f764b4ea5437ea707fdebd6
Quellennotizuspto-grants-2014_09