Methyl 2-chloropyrimidine-5-carboxylate → 2-{4-[Cyclopropyl-(4-oxazol-5-yl-benzoyl)-amino]-piperidin-1-yl}-pyrimidine-5-carboxylic acid methyl ester

Beteiligte Stoffe

Reaktionsschritte

The title compound is prepared from N-cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide hydrochloride and 2-chloro-pyrimidine-5-carboxylic acid methyl ester following a procedure analogous to that described in Example 19 using N-methylpyrrolidinone as solvent. LC (method 16): tR=0.48 min; Mass spectrum (ESI+): m/z=448 [M+H]+.

Herkunft & Nachweise