6-{[6-(1-Methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl}quinoline → 3-(1h-Indazol-5-ylmethyl)-6-(1-methyl-1h-pyrazol-4-yl)-imidazo[1,2-b]pyridazine
Reaktionsgleichung
CN1C=C(C2C=CC3N(C(CC4C=C5C(=CC=4)N=CC=C5)=CN=3)N=2)C=N1.[NH:27]1[C:35]2[C:30](=[CH:31][C:32]([CH:36]([C:38]3[N:42]4[N:43]=[C:44]([C:47]5[CH:48]=[N:49][N:50]([CH3:52])[CH:51]=5)[CH:45]=[CH:46][C:41]4=[N:40][CH:39]=3)O)=[CH:33][CH:34]=2)[CH:29]=[N:28]1>>[NH:27]1[C:35]2[C:30](=[CH:31][C:32]([CH2:36][C:38]3[N:42]4[N:43]=[C:44]([C:47]5[CH:48]=[N:49][N:50]([CH3:52])[CH:51]=5)[CH:45]=[CH:46][C:41]4=[N:40][CH:39]=3)=[CH:33][CH:34]=2)[CH:29]=[N:28]1Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
The title compound was prepared in analogy to the synthesis of compound of Example 2 using (rac)-(1H-Indazol-5-yl)-[6-(1-methyl-1H-pyrazol-4-yl)-imidazo[1,2-b]pyridazin-3-yl]-methanol (Stage 150.1) as starting material (tR 1.10 min (conditions 2), MH+=330).