4-Butoxy-2-methylbenzoic acid → 4-butoxy-N-[4-(3-dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-2-methylbenzamide

HRID 69424Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 69424
[CH2:1]([O:5][C:6]1[CH:14]=[CH:13][C:9]([C:10]([OH:12])=O)=[C:8]([CH3:15])[CH:7]=1)[CH2:2][CH2:3][CH3:4].[NH2:16][C:17]1[CH:22]=[CH:21][C:20]([N:23]2[CH2:27][CH2:26][CH:25]([N:28]([CH3:30])[CH3:29])[CH2:24]2)=[C:19]([F:31])[CH:18]=1>>[CH2:1]([O:5][C:6]1[CH:14]=[CH:13][C:9]([C:10]([NH:16][C:17]2[CH:22]=[CH:21][C:20]([N:23]3[CH2:27][CH2:26][CH:25]([N:28]([CH3:29])[CH3:30])[CH2:24]3)=[C:19]([F:31])[CH:18]=2)=[O:12])=[C:8]([CH3:15])[CH:7]=1)[CH2:2][CH2:3][CH3:4]

Komponenten

3

Edukt 2

HCID 534398994-Butoxy-2-methylbenzoic acidHCID 631640961-(4-amino-2-fluorophenyl)-N,N-dimethylpyrrolidin-3-amine

Produkt 1

HCID 689905684-butoxy-N-[4-(3-dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-2-methylbenzamide

Versuchsvorschrift

4-Butoxy-2-methylbenzoic acid was reacted with [1-(4-amino-2-fluorophenyl)pyrrolidin-3-yl]dimethylamine by method P. The product with the molecular weight of 413.54 (C24H32FN3O2) was obtained in this way; MS (ESI): 414 (M+H+).

Aufarbeitung

  1. customThe product with the molecular weight of 413.54 (C24H32FN3O2) was obtained in this way

Quellen und Nachweise

ORD-Eintrag
ord-2d49735783f44953acbd31bf56fd6fc6
Quelldatensatz
uspto-grants-2014_09
Patentnummer
US08822495B2

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