Methyl iodide → 2-((R)-4-[1,3']Bipyrrolidinyl-1'-yl-3-fluorophenyl)-6-(2-methoxy-butoxy)-2H-isoquinolin-1-one
Reaktionsgleichung
[N:1]1([C@@H:6]2[CH2:10][CH2:9][N:8]([C:11]3[CH:16]=[CH:15][C:14]([N:17]4[CH:26]=[CH:25][C:24]5[C:19](=[CH:20][CH:21]=[C:22]([O:27][CH2:28][CH:29]([OH:32])[CH2:30][CH3:31])[CH:23]=5)[C:18]4=[O:33])=[CH:13][C:12]=3[F:34])[CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:35]I>>[N:1]1([C@@H:6]2[CH2:10][CH2:9][N:8]([C:11]3[CH:16]=[CH:15][C:14]([N:17]4[CH:26]=[CH:25][C:24]5[C:19](=[CH:20][CH:21]=[C:22]([O:27][CH2:28][CH:29]([O:32][CH3:35])[CH2:30][CH3:31])[CH:23]=5)[C:18]4=[O:33])=[CH:13][C:12]=3[F:34])[CH2:7]2)[CH2:2][CH2:3][CH2:4][CH2:5]1Komponenten
3
Versuchsvorschrift
According to Method AA, 2-((R)-4-[1,3′]bipyrrolidinyl-1′-yl-3-fluorophenyl)-6-(2-hydroxy-butoxy)-2H-isoquinolin-1-one was reacted with methyl iodide. In this way the product was obtained with molecular weight 479.60 (C28H34FN3O3); MS (ESI): 480 (M+H+).
Aufarbeitung
- customIn this way the product was obtained with molecular weight 479.60 (C28H34FN3O3)