(S)-1-(tetrahydrofuran-2-yl)methyl methanesulfonate → 6-[(S)-1-(Tetrahydrofuran-2-yl)methoxy]isochroman-1-one
Reaktionsgleichung
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[O:7][CH2:6][CH2:5]2.[O:13]1[CH2:17][CH2:16][CH2:15][C@H:14]1[CH2:18]OS(C)(=O)=O>>[O:13]1[CH2:17][CH2:16][CH2:15][C@H:14]1[CH2:18][O:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[O:7][CH2:6][CH2:5]2Komponenten
3
Versuchsvorschrift
6-Hydroxy-isochroman-1-one was reacted with Methanesulfonic acid (S)-1-(tetrahydro-furan-2-yl)methyl ester by method K1. The product with the molecular weight of 248.28 (C14H28FN3O3) was obtained in this way; MS (ESI): 249 (M+H+).
Aufarbeitung
- customThe product with the molecular weight of 248.28 (C14H28FN3O3) was obtained in this way
Quellen und Nachweise
- ORD-Eintrag
- ord-9f1b5cd813824eb0918c0a20c665674d
- Quelldatensatz
- uspto-grants-2014_09
- Patentnummer
- US08822495B2
Notizen zur Reaktion
Wird geladen…