HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Chloro-3-nitrobenzophenone → Tert-butyl 4-(4-benzoyl-2-nitrophenyl)piperazine-1-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Chloro-3-nitrobenzophenone | HCID 41743 | — |
| Edukt | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Lösungsmittel | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Produkt | Tert-butyl 4-(4-benzoyl-2-nitrophenyl)piperazine-1-carboxylate | HCID 69045013 | 93% |
Reaktionsschritte
Method 1 was followed using 4-chloro-3-nitrobenzophenone (1.0 eq), 1-Boc-piperazine (1.1 eq), and TEA (2.0 eq) in NMP yielding tert-butyl 4-(4-benzoyl-2-nitrophenyl)piperazine-1-carboxylate (93%). LCMS (m/z): 412.2 (MH+); LC Rt=3.59 min.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08822497B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-6248ee4f40be43a3b83ec9a4dcedc2ad |
| Quellennotiz | uspto-grants-2014_09 |