HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tert-butyl 4-(2-nitro-4-(trifluoromethyl)phenyl)piperazine-1-carboxylate → tert-Butyl 4-[2-amino-4-(trifluoromethyl)phenyl]piperazine-1-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tert-butyl 4-(2-nitro-4-(trifluoromethyl)phenyl)piperazine-1-carboxylate | HCID 53426214 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | tert-Butyl 4-[2-amino-4-(trifluoromethyl)phenyl]piperazine-1-carboxylate | HCID 53426177 | 99% |
Reaktionsschritte
Following the method of Example 49 (Method 2), tert-butyl 4-(2-nitro-4-(trifluoro-methyl)phenyl)piperazine-1-carboxylate in MeOH was reduced yielding tert-butyl 4-(2-amino-4-(trifluoromethyl)phenyl)piperazine-1-carboxylate (99%). LCMS (m/z): 346.1 (MH+); LC Rt=3.38 min.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08822497B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-05943aaf658c44c99e7446df3ab7a65b |
| Quellennotiz | uspto-grants-2014_09 |