HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-Aminobenzothiazole → 4-Nitrophenyl benzo[d]thiazol-6-ylcarbamate hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 6-Aminobenzothiazole | HCID 68288 | — |
| Edukt | 4-Nitrophenyl chloroformate | HCID 82129 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 4-Nitrophenyl benzo[d]thiazol-6-ylcarbamate hydrochloride | HCID 66797303 | 81% |
Reaktionsschritte
6-Aminobenzothiazole (100 mg, 0.666 mmol) and p-nitrophenyl chloroformate (148 mg, 0.733 mmol) were stirred at rt in CH2Cl2 (5 mL) overnight. The resulting solid was collected by filtration, yielding 183 mg (81%) of the title compound. LC-MS: RT=8.17 min, [M+H]+=316.0.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08822472B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-5b5b00a8a2234c6e86c3e37c49c0c5b4 |
| Quellennotiz | uspto-grants-2014_09 |