HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dichloromethane → 3-(2,2,3,3,3-Pentafluoropropoxy)methyl-4-methyl-1-nitrobenzene
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dichloromethane | HCID 6344 | — |
| Edukt | 2,2,3,3,3-Pentafluoropropanol | HCID 9872 | — |
| Edukt | Potassium Hydroxide | HCID 14797 | — |
| Edukt | 2-(Chloromethyl)-1-methyl-4-nitrobenzene | HCID 187952 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 3-(2,2,3,3,3-Pentafluoropropoxy)methyl-4-methyl-1-nitrobenzene | HCID 15070168 | — |
Reaktionsschritte
In 16.5 ml of dimethylformamide, 5.00 g (0.027 mol) of 2-methyl-5-nitrobenzyl chloride and 21.3 g (0.135 mol) of 2,2,3,3,3-pentafluoropropanol were dissolved. The solution was then added with 2.29 g (0.041 mol) of KOH pellets and stirred overnight. Dichloromethane was added and the precipitated salts were filtered out. The filtrate was acidified with dilute hydrochloric acid and then the solvents were distilled off.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04983209 |
| Quelldatensatz | uspto-grants-1991_01 |
| ORD ID | ord-fe6198eb9b0a45a8ba52b72219df5ea0 |
| Quellennotiz | uspto-grants-1991_01 |