HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Morpholinoethylamine → N-[2-(4-Morpholinyl)ethyl]-4-methylpyridazino[4,5-b]indolizin-1-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Morpholinoethylamine | HCID 408285 | — |
| Edukt | 1-Chloro-4-methylpyridazino[4,5-b]indolizine | HCID 15713312 | — |
| Produkt | N-[2-(4-Morpholinyl)ethyl]-4-methylpyridazino[4,5-b]indolizin-1-amine | HCID 15713315 | — |
Reaktionsschritte
Following the procedure of Example 1, reaction of one equivalent of 1-chloro-4-methylpyridazino[4,5-b]indolizine and 27 equivalents of 4-(2-aminoethyl)morpholine gave the title compound as the free base which was converted to the dihydrochloride salt (MeOH/ethereal HCl/diethyl ether), mp 310° C. (dec).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04985560 |
| Quelldatensatz | uspto-grants-1991_01 |
| ORD ID | ord-ed30324bb00c4b04b2db11ae77c59b13 |
| Quellennotiz | uspto-grants-1991_01 |