HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-(3-Aminopropyl)morpholine → N-[3-(4-Morpholinyl)propyl]-4-methylpyridazino[4,5-b]indolizin-1-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-(3-Aminopropyl)morpholine | HCID 61055 | — |
| Edukt | 1-Chloro-4-methylpyridazino[4,5-b]indolizine | HCID 15713312 | — |
| Produkt | N-[3-(4-Morpholinyl)propyl]-4-methylpyridazino[4,5-b]indolizin-1-amine | HCID 15713316 | — |
Reaktionsschritte
Following the procedure of Example 1, reaction of one equivalent of 1-chloro-4-methylpyridazino[4,5-b]indolizine and 10 equivalents of 4-(3-aminopropyl)morpholine gave the title compound as the free base which was converted to the dihydrochloride salt, mp. 295°-296° C. (after recrystallization from ethanol).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04985560 |
| Quelldatensatz | uspto-grants-1991_01 |
| ORD ID | ord-a6000ef64477480795ef1f47757fc758 |
| Quellennotiz | uspto-grants-1991_01 |