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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 704827Erstellt: 25. Oktober 2026

N,N-Diethyl-1,3-propanediamine → N-[3-(diethylamino)propyl]-4,5-bis(4-fluorophenyl)-1H-pyrazole-1-acetamide

https://huagongshe.com/reaction/704827

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktN,N-Diethyl-1,3-propanediamineHCID 61011—
Eduktethyl 4,5-bis(4-fluorophenyl)-1H-pyrazole-1-acetateHCID 14699554—
ProduktN-[3-(diethylamino)propyl]-4,5-bis(4-fluorophenyl)-1H-pyrazole-1-acetamideHCID 2007328145,4%

Reaktionsschritte

By a procedure substantially similar to that of Example 14, 8 g (0.023 mol) of ethyl 4,5-bis(4-fluorophenyl)-1H-pyrazole-1-acetate of Example 3 and 34.3 mL (0.22 mol) of diethylaminopropylamine were reacted to produce 4.45 g of N-[3-(diethylamino)propyl]-4,5-bis(4-fluorophenyl)-1H-pyrazole-1-acetamide. The solid product after trituration in water collapsed to a non-crystalline, white, waxy solid upon drying.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04988725
Quelldatensatzuspto-grants-1991_01
ORD IDord-d3b6380771a74693b629e5a61c38f691
Quellennotizuspto-grants-1991_01