N-bromobutanimide → 4-(Hydroxyimino-bromomethyl)-benzonitrile

HRID 708943Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 708943
[Br:1]N1C(=O)CCC1=O.[OH:9][N:10]=[CH:11][C:12]1[CH:19]=[CH:18][C:15]([C:16]#[N:17])=[CH:14][CH:13]=1>C(Cl)Cl>[OH:9][N:10]=[C:11]([Br:1])[C:12]1[CH:19]=[CH:18][C:15]([C:16]#[N:17])=[CH:14][CH:13]=1

Komponenten

4

Edukt 2

HCID 67184N-bromobutanimideHCID 52147424-Cyanobenzaldehyde oxime

Produkt 1

HCID 867199294-(Hydroxyimino-bromomethyl)-benzonitrile

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel2×

Versuchsvorschrift

The compound was prepared according to Tanaka et al. Bull. Chem. Soc. Jpn. 1984, 57, 2184. A 0.05M solution of N-bromosuccinimide (724 mg, 4.07 mmol, 1.20 eq) in CH2Cl2 was added dropwise to a 0° C. solution of 4-(hydroxyiminomethyl)-benzonitrile (496 mg, 3.39 mmol, 1.00 eq) in CH2Cl2 (50 mL). The solution was warmed to room temperature before being volumetrically partitioned between two different reaction vials. Each vial was then concentrated and the crude residues were used without further purification.

Aufarbeitung

  1. customThe compound was prepared
  2. custombefore being volumetrically partitioned between two different reaction vials
  3. concentrationEach vial was then concentrated
  4. customthe crude residues were used without further purification

Quellen und Nachweise

ORD-Eintrag
ord-312b7c46ea924744ba95f60d5869529c
Quelldatensatz
uspto-grants-2015_11
Patentnummer
US09179681B2

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