Benzonatate → Benzonatate calcium silicate

Beteiligte Stoffe

Reaktionsschritte

Calcium silicate was mixed at slow speed in a high shear granulator (Impeller: 250 rpm and Chopper: 3200 rpm). Benzonatate was added to it at slow speed (Impeller: 250 rpm and Chopper: 3200 rpm) at a rate of approximately 7 g/minute. The benzonatate-calcium silicate adsorbate granules formed were passed through 425 micron screen and assayed as described above for benzonatate content.

Herkunft & Nachweise