Selenium Dioxide → Methyl 2-((1R,2S)-2-(tert-butoxycarbonylamino)cyclohexylamino)-4-formyl-6-(1-methyl-1H-pyrazol-4-yl)pyrimidine-5-carboxylate
Reaktionsgleichung
[C:1]([O:5][C:6]([NH:8][C@H:9]1[CH2:14][CH2:13][CH2:12][CH2:11][C@H:10]1[NH:15][C:16]1[N:21]=[C:20]([CH3:22])[C:19]([C:23]([O:25][CH3:26])=[O:24])=[C:18]([C:27]2[CH:28]=[N:29][N:30]([CH3:32])[CH:31]=2)[N:17]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[Se](=O)=[O:34]>O1CCOCC1>[C:1]([O:5][C:6]([NH:8][C@H:9]1[CH2:14][CH2:13][CH2:12][CH2:11][C@H:10]1[NH:15][C:16]1[N:21]=[C:20]([CH:22]=[O:34])[C:19]([C:23]([O:25][CH3:26])=[O:24])=[C:18]([C:27]2[CH:28]=[N:29][N:30]([CH3:32])[CH:31]=2)[N:17]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]Komponenten
4
Reaktionsbedingungen
- Temperatur
- 100 °C