2-Benzyl-hexahydro-cyclopenta[c]pyrrole-3a-carboxylic acid methyl ester → Methyl octahydrocyclopenta[c]pyrrole-3a-carboxylate

Beteiligte Stoffe

Reaktionsschritte

To a stirred solution of methyl 2-benzyloctahydrocyclopenta[c]pyrrole-3a-carboxylate (2.0 g, 7.69 mmol) in MeOH (15.0 mL) was added palladium hydroxide (0.20 g, 10% w/w) and the mixture stirred at rt for 16 h under H2 atmosphere. After completion of reaction (by TLC), the reaction mixture was passed through celite and the solvent evaporated. The crude (1.50 g) residue was carried forward for the next step without further purification. MS: 170.18 [M+H]+.

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