1,1'-Carbonyldiimidazole → methyl 3-{(5S,7S)-7-[(6-cyano-1H-benzimidazol-1-yl)methyl]-2-oxo-1-oxa-3-azaspiro[4.5]dec-3-yl}-2,2-dimethylpropanoate
Reaktionsgleichung
[C:1]([C:3]1[CH:4]=[CH:5][C:6]2[N:10]=[CH:9][N:8]([CH2:11][CH:12]3[CH2:17][CH2:16][CH2:15][C:14]([CH2:19][NH:20][CH2:21][C:22]([CH3:28])([CH3:27])[C:23]([O:25][CH3:26])=[O:24])([OH:18])[CH2:13]3)[C:7]=2[CH:29]=1)#[N:2].C1N=CN([C:35](N2C=NC=C2)=[O:36])C=1>O1CCOCC1>[C:1]([C:3]1[CH:4]=[CH:5][C:6]2[N:10]=[CH:9][N:8]([CH2:11][C@H:12]3[CH2:17][CH2:16][CH2:15][C@:14]4([O:18][C:35](=[O:36])[N:20]([CH2:21][C:22]([CH3:27])([CH3:28])[C:23]([O:25][CH3:26])=[O:24])[CH2:19]4)[CH2:13]3)[C:7]=2[CH:29]=1)#[N:2]Komponenten
4
