HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Chloro-4-fluorobenzoic acid → 3-chloro-4-fluoro-N-isopropylbenzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Chloro-4-fluorobenzoic acid | HCID 520989 | — |
| Edukt | 2-Propanamine, hydrochloride (1:1) | HCID 6432137 | — |
| Produkt | 3-chloro-4-fluoro-N-isopropylbenzamide | HCID 58324493 | 81% |
Reaktionsschritte
Using isopropylamine hydrochloride and 3-chloro-4-fluorobenzoic acid in the general procedure for coupling of amines to carboxylic acids, the title compound was obtained (81% yield) as a white solid. ESI-MS: m/z 216 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09187497B2 |
| Quelldatensatz | uspto-grants-2015_11 |
| ORD ID | ord-ebbc72c550fb43978536b470af1cfceb |
| Quellennotiz | uspto-grants-2015_11 |