2-Chloromethyl 2-(trimethylsilyl)ethyl ether → HCID 131734178, Verbindung
Reaktionsgleichung
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12](=[O:13])[NH:11][N:10]=[N:9]2)=[CH:4][CH:3]=1.[CH3:14][Si:15]([CH2:18][CH2:19][O:20][CH2:21]Cl)([CH3:17])[CH3:16]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[C:12](=[O:13])[N:11]([CH2:21][O:20][CH2:19][CH2:18][Si:15]([CH3:17])([CH3:16])[CH3:14])[N:10]=[N:9]2)=[CH:6][CH:7]=1Komponenten
3
Versuchsvorschrift
Compound 53a was treated with SEMCl as described in Example 51, Step C to obtain compound 53b as a white solid. Mass Spectrum (LCMS, ESI pos.): Calcd. for C13H19BrN4O2Si: 371.0 (M+H). Found 371.1.
Quellen und Nachweise
- ORD-Eintrag
- ord-1b06f4f8f07e400eb0f0f403ace73653
- Quelldatensatz
- uspto-grants-2015_11
- Patentnummer
- US09193736B2
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