(Ethoxy-phenyl-phosphinoyl)-hydroxy-acetic acid ethyl ester → Hydroxy-(hydroxy-phenyl-phosphinoyl)-acetic acid
Reaktionsgleichung
C([O:3][C:4](=[O:18])[CH:5]([P:7]([O:15]CC)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8])[OH:6])C>Cl>[OH:6][CH:5]([P:7]([OH:15])([C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)=[O:8])[C:4]([OH:18])=[O:3]Komponenten
3
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of (ethoxy-phenyl-phosphinoyl)-hydroxy-acetic acid ethyl ester (382 mg, 1.41 mmol) in 10 mL of 6 M HCl was heated to reflux overnight. The resulting mixture was concentrated to a minimum volume and lyophilized affording a pale yellow solid (274 mg, 90%)
Aufarbeitung
- temperatureto reflux overnight
- concentrationThe resulting mixture was concentrated to a minimum volume
Quellen und Nachweise
- ORD-Eintrag
- ord-34c1623f03e244e5b8e4ecf5c9606076
- Quelldatensatz
- uspto-grants-2006_11
- Patentnummer
- US07132427B2
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