4-(2-chloro-5-nitrophenyl)-1,3-thiazol-2-amine hydrobromide → HCID 10116602, Verbindung
Reaktionsgleichung
Br.[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]([O-:11])=[O:10])=[CH:5][C:4]=1[C:12]1[N:13]=[C:14]([NH2:17])[S:15][CH:16]=1.[Cl:18][C:19]1[CH:24]=[C:23]([Cl:25])[CH:22]=[C:21]([CH3:26])[C:20]=1[S:27](Cl)(=[O:29])=[O:28]>>[Cl:18][C:19]1[CH:24]=[C:23]([Cl:25])[CH:22]=[C:21]([CH3:26])[C:20]=1[S:27]([NH:17][C:14]1[S:15][CH:16]=[C:12]([C:4]2[CH:5]=[C:6]([N+:9]([O-:11])=[O:10])[CH:7]=[CH:8][C:3]=2[Cl:2])[N:13]=1)(=[O:29])=[O:28]Komponenten
3
Versuchsvorschrift
The title compound was prepared from 4-(2-chloro-5-nitrophenyl)-1,3-thiazol-2-amine hydrobromide and 2,4-dichloro-6-methylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a white-yellow solid (18.4 mg) with purity >90%. MS (pos) m/z 478.0, 479.9.
Quellen und Nachweise
- ORD-Eintrag
- ord-8f49bd35c3964d938070562f37ab1ac0
- Quelldatensatz
- uspto-grants-2006_11