2,3,4-Trimethoxybenzaldehyde → 6,7,8-Trimethoxynaphthalene-2-carbonitrile

Reaktionsgleichung

[CH3:1][O:2][C:3]1[C:10]([O:11][CH3:12])=[C:9]([O:13][CH3:14])[CH:8]=[CH:7][C:4]=1[CH:5]=O.CO[CH:17](OC)[CH2:18][CH2:19][C:20]#[N:21]>>[CH3:14][O:13][C:9]1[CH:8]=[C:7]2[C:4](=[C:3]([O:2][CH3:1])[C:10]=1[O:11][CH3:12])[CH:5]=[C:19]([C:20]#[N:21])[CH:18]=[CH:17]2

Komponenten

Edukt 2

HCID 750062,3,4-Trimethoxybenzaldehyde

HCID 845584,4-Dimethoxybutyronitrile

Produkt 1

HCID 218916206,7,8-Trimethoxynaphthalene-2-carbonitrile

Versuchsvorschrift

2,3,4-Trimethoxybenzaldehyde (9.8 g) and 3-cyanopropionaldehyde dimethylacetal (6.35 mL) were treated under the same conditions as in Preparation Example 1 to obtain the title compound.

Quellen und Nachweise

ORD-Eintrag: ord-8773f843b97e4634a9821e7af0e2fd66
Quelldatensatz: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07135473B2

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