Hexahydro-1,4-diazepine → N,N'-bis(5,6,7-trimethoxyindole-2-carbonyl)homopiperazine

HRID 720330

Reaktionsgleichung

Reaktionsgleichung von HRID 720330
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[C:10]([O:14][CH3:15])[C:11]=1[O:12][CH3:13])[NH:8][C:7]([C:16]([OH:18])=O)=[CH:6]2.[NH:19]1[CH2:25][CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[C:10]([O:14][CH3:15])[C:11]=1[O:12][CH3:13])[NH:8][C:7]([C:16]([N:19]1[CH2:25][CH2:24][CH2:23][N:22]([C:16]([C:7]3[NH:8][C:9]4[C:5]([CH:6]=3)=[CH:4][C:3]([O:2][CH3:1])=[C:11]([O:12][CH3:13])[C:10]=4[O:14][CH3:15])=[O:18])[CH2:21][CH2:20]1)=[O:18])=[CH:6]2

Komponenten

3

Edukt 2

HCID 68163Hexahydro-1,4-diazepineHCID 8210525,6,7-Trimethoxy-1H-indole-2-carboxylic acid

Produkt 1

HCID 21891614N,N'-bis(5,6,7-trimethoxyindole-2-carbonyl)homopiperazine

Versuchsvorschrift

5,6,7-Trimethoxyindole-2-carboxylic acid (300 mg) and homopiperazine (60 mg) were reacted in the same manner as in Preparation Example 37 to obtain the title compound.

Quellen und Nachweise

ORD-Eintrag
ord-392f872bb6ae4481bdcdcb41aa502896
Quelldatensatz
uspto-grants-2006_11
Patentnummer
US07135473B2

Verknüpfte Notizen

Wird geladen…