HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → (R)-2-adamantyl 3-aminopyrrolidine-1-carboxylate HCl salt
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | 1,4-Dioxane | HCID 31275 | — |
| Edukt | (3R)-(2-adamantyl) 3-(tert-butoxycarbonylamino)pyrrolidine-1-carboxylate | HCID 52944645 | — |
| Produkt | (R)-2-adamantyl 3-aminopyrrolidine-1-carboxylate HCl salt | HCID 67155574 | — |
Reaktionsschritte
To (3R)-(2-adamantyl) 3-(tert-butoxycarbonylamino)pyrrolidine-1-carboxylate (0.43 g, 1.18 mmol) was added 4 M HCl in dioxane (5 mL, 20 mmol). The mixture was stirred at rt for 1 h and concentrated to afford (R)-2-adamantyl 3-aminopyrrolidine-1-carboxylate HCl salt (0.45 g) as a white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08828985B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-32c85c6786cb4689912a002dee8a1170 |
| Quellennotiz | uspto-grants-2014_09 |