2-Chloro-4,5-difluorobenzoyl Isocyanate → HCID 178488186, Verbindung

HRID 722202

Reaktionsgleichung

Reaktionsgleichung von HRID 722202
[Cl:1][C:2]1[CH:12]=[C:11]([F:13])[C:10]([F:14])=[CH:9][C:3]=1[C:4]([N:6]=[C:7]=[O:8])=[O:5].[CH3:15][O:16][C:17]1[CH:22]=[C:21]([C:23]2[NH:27][C:26]([CH3:28])=[N:25][N:24]=2)[CH:20]=[CH:19][C:18]=1[NH2:29]>C(#N)C>[Cl:1][C:2]1[CH:12]=[C:11]([F:13])[C:10]([F:14])=[CH:9][C:3]=1[C:4]([NH:6][C:7]([NH:29][C:18]1[CH:19]=[CH:20][C:21]([C:23]2[NH:27][C:26]([CH3:28])=[N:25][N:24]=2)=[CH:22][C:17]=1[O:16][CH3:15])=[O:8])=[O:5]

Komponenten

4

Edukt 2

HCID 115575832-Chloro-4,5-difluorobenzoyl IsocyanateHCID 178488184HCID 178488184, Verbindung

Produkt 1

HCID 178488186HCID 178488186, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel

Versuchsvorschrift

The solution of equivalent amounts of 2-chloro-4,5-difluorobenzoyl isocyanate was added dropwise to the solution of 30 mg of 2-methoxy-4-(5-methyl-4H-[1,2,4]triazol-3-yl)phenylamine in 3 ml of acetonitrile and the mixture was stirred at room temperature for 30 minutes. The solid was then filtered off with suction, stirred with isopropanol and dried under reduced pressure.

Aufarbeitung

  1. filtrationThe solid was then filtered off with suction
  2. stirringstirred with isopropanol
  3. customdried under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-9d63ce9c4ae741549cc6f9bc5d723dc6
Quelldatensatz
uspto-grants-2006_11
Patentnummer
US07138414B2

Verknüpfte Notizen

Wird geladen…