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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 722215Erstellt: 26. Oktober 2026

5-(3-Methoxy-4-nitrophenyl)-1,3,4-oxadiazol-2(3H)-one → 5-(4-Amino-3-methoxyphenyl)-1,3,4-oxadiazol-2(3H)-one

https://huagongshe.com/reaction/722215

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt5-(3-Methoxy-4-nitrophenyl)-1,3,4-oxadiazol-2(3H)-oneHCID 21883906—
EduktHCID 178418361HCID 178418361—
KatalysatorPalladiumHCID 23938—
LösungsmittelTetrahydrofuranHCID 8028—
Produkt5-(4-Amino-3-methoxyphenyl)-1,3,4-oxadiazol-2(3H)-oneHCID 21883858—

Reaktionsschritte

Hydrogen was introduced under atmospheric pressure into the mixture of 550 mg of 5-(3-methoxy-4-nitrophenyl)-3H-[1,3,4]oxadiazol-2-one, 100 mg of Pd/C and 50 ml of THF up to the theoretical uptake. Afterwards, the catalyst was filtered off with suction and the mixture was concentrated to dryness under reduced pressure.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07138414B2
Quelldatensatzuspto-grants-2006_11
ORD IDord-d939b21e53a944c3aa5ddfdff4b7cc5a
Quellennotizuspto-grants-2006_11