2-Amino-4-(trifluoromethyl)phenol → N-(2-Hydroxy-5-trifluoromethylphenyl)-2-fluoro-5-nitrobenzamide

HRID 722580

Reaktionsgleichung

Reaktionsgleichung von HRID 722580
[NH2:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[OH:12].[F:13][C:14]1[CH:22]=[CH:21][C:20]([N+:23]([O-:25])=[O:24])=[CH:19][C:15]=1[C:16](Cl)=[O:17]>>[OH:12][C:3]1[CH:4]=[CH:5][C:6]([C:8]([F:9])([F:10])[F:11])=[CH:7][C:2]=1[NH:1][C:16](=[O:17])[C:15]1[CH:19]=[C:20]([N+:23]([O-:25])=[O:24])[CH:21]=[CH:22][C:14]=1[F:13]

Komponenten

3

Edukt 2

HCID 1202462-Amino-4-(trifluoromethyl)phenolHCID 109765702-Fluoro-5-nitrobenzoyl chloride

Produkt 1

HCID 21884558N-(2-Hydroxy-5-trifluoromethylphenyl)-2-fluoro-5-nitrobenzamide

Versuchsvorschrift

Prepared by the method of Example 15a), from 2-amino-4-trifluoromethylphenol (407 mg, 2.3 mmol) and 2-fluoro-5-nitrobenzoyl chloride (468 mg, 2.3 mmol) the subtitle compound was obtained. The product was used directly in the next step without purification.

Quellen und Nachweise

ORD-Eintrag
ord-d529938645dc4604aa966d30da2ea4c8
Quelldatensatz
uspto-grants-2006_11
Patentnummer
US07138425B2

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